Teichoic acids: antigenic determinants, chain separation, and their location in the cell wall.
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چکیده
منابع مشابه
Teichoic acids: antigenic determinants, chain separation, and their location in the cell wall.
Teichoic acids are linear polymers of glycerophosphate or ribitolphosphate carrying sugar or D-alanine substituents.1 Their chain length varies between 8 and 50 units and is dependent upon the isolation technique. Some occur in bacterial cell walls where they can make up between 8 and 50 per cent of the wall's dry weight; some, the so-called "intracellular" ones, in an ill-defined area between ...
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Data on the structures of cell wall teichoic acids, the anionic carbohydrate-containing polymers, found in many Gram-positive bacteria have been summarized and the polymers of the actinomycete genus Nocardiopsis have been considered from the taxonomic standpoint. The structures of these polymers or their combinations have been demonstrated to be indicative of each of seven Nocardiopsis species ...
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15 صفحه اولMethicillin resistance in Staphylococcus aureus requires glycosylated wall teichoic acids.
Staphylococcus aureus peptidoglycan (PG) is densely functionalized with anionic polymers called wall teichoic acids (WTAs). These polymers contain three tailoring modifications: d-alanylation, α-O-GlcNAcylation, and β-O-GlcNAcylation. Here we describe the discovery and biochemical characterization of a unique glycosyltransferase, TarS, that attaches β-O-GlcNAc (β-O-N-acetyl-D-glucosamine) resid...
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PURPOSE Wall teichoic acids (WTAs) are major polyanionic polymer components of the cell wall of Staphylococcus aureus. However, little is known about their role at the host-pathogen interface, especially in endophthalmitis. This study was designed to investigate the extent to which WTAs contribute to the pathogenicity of S. aureus in models of endophthalmitis and to determine whether there woul...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1966
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.56.3.910